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s1 fc proteins  (Sino Biological)


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    Sino Biological s1 fc proteins
    S1 Fc Proteins, supplied by Sino Biological, used in various techniques. Bioz Stars score: 95/100, based on 79 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/s1 fc proteins/product/Sino Biological
    Average 95 stars, based on 79 article reviews
    s1 fc proteins - by Bioz Stars, 2026-02
    95/100 stars

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    Image Search Results


    Omicron S1 shows reduced immune cells recruitment and expansion compared with the ancestral variant. Recombinant S1WT, S1 Omicron or vehicle (-) were injected in the hindbrain ventricle (HBV) of Tg(lyz:DsRED) (A) , Tg(mfap4:Tomato) (B) , Tg(nfkb:eGFP) (C) of 2-dpf larvae. Neutrophil (A) and macrophage (B) recruitment and number and Nfkb reporter activity (C) were analyzed at 6, 12, and/or 24 hpi by fluorescence microscopy. Representative photos for each treatment are shown from 24 hpi. Scale bar 500 μm. Each dot represents one individual, and the means ± SEM for each group is also shown. P values were calculated using one-way analysis of variance (ANOVA) and Tukey multiple range test. ns, not significant; * P ≤ 0.05, ** P ≤ 0.01, *** P ≤ 0.001 and **** p < 0.0001. auf, arbitrary units of fluorescence.

    Journal: Frontiers in Immunology

    Article Title: Dual role of ACE2 in regulating inflammation triggered by Omicron S1 and other SARS-CoV-2 Spike variants

    doi: 10.3389/fimmu.2025.1667880

    Figure Lengend Snippet: Omicron S1 shows reduced immune cells recruitment and expansion compared with the ancestral variant. Recombinant S1WT, S1 Omicron or vehicle (-) were injected in the hindbrain ventricle (HBV) of Tg(lyz:DsRED) (A) , Tg(mfap4:Tomato) (B) , Tg(nfkb:eGFP) (C) of 2-dpf larvae. Neutrophil (A) and macrophage (B) recruitment and number and Nfkb reporter activity (C) were analyzed at 6, 12, and/or 24 hpi by fluorescence microscopy. Representative photos for each treatment are shown from 24 hpi. Scale bar 500 μm. Each dot represents one individual, and the means ± SEM for each group is also shown. P values were calculated using one-way analysis of variance (ANOVA) and Tukey multiple range test. ns, not significant; * P ≤ 0.05, ** P ≤ 0.01, *** P ≤ 0.001 and **** p < 0.0001. auf, arbitrary units of fluorescence.

    Article Snippet: Recombinant His-tagged Spike S1 wild-type (#40591-V08B1), S1 Omicron (#40592-V08H121) or Spike S1/S2 TRIMER wild-type (#40589-V08H8), all from Sino Biological at a concentration of 0.25 mg/ml supplemented with phenol red were injected into the hindbrain (1 nl) of 48 hpf zebrafish larvae.

    Techniques: Variant Assay, Recombinant, Injection, Activity Assay, Fluorescence, Microscopy

    Omicron is more proinflammatory than the ancestral variant. Recombinant S1WT, S1 Omicron or vehicle (-) were injected in the hindbrain ventricle (HBV) of WT (A–F) 2-dpf larvae. The transcript levels of the indicated genes (A–E) were analyzed at 12 hpi by RT-qPCR in larval head and rest of the body and caspase-1 activity was determined at 24 hpi using a fluorogenic substrate (F) . Graphs shown are representative of three independent experiments; technical replicates are displayed in each graph. The means ± SEM for each group is shown. P values were calculated using one-way analysis of variance (ANOVA) and Tukey multiple range test. n=45 in (A–E) , n=35 in (F) . ns, not significant; * P ≤ 0.05, ** P ≤ 0.01, *** P ≤ 0.001 and **** p < 0.0001. auf, arbitrary units of fluorescence.

    Journal: Frontiers in Immunology

    Article Title: Dual role of ACE2 in regulating inflammation triggered by Omicron S1 and other SARS-CoV-2 Spike variants

    doi: 10.3389/fimmu.2025.1667880

    Figure Lengend Snippet: Omicron is more proinflammatory than the ancestral variant. Recombinant S1WT, S1 Omicron or vehicle (-) were injected in the hindbrain ventricle (HBV) of WT (A–F) 2-dpf larvae. The transcript levels of the indicated genes (A–E) were analyzed at 12 hpi by RT-qPCR in larval head and rest of the body and caspase-1 activity was determined at 24 hpi using a fluorogenic substrate (F) . Graphs shown are representative of three independent experiments; technical replicates are displayed in each graph. The means ± SEM for each group is shown. P values were calculated using one-way analysis of variance (ANOVA) and Tukey multiple range test. n=45 in (A–E) , n=35 in (F) . ns, not significant; * P ≤ 0.05, ** P ≤ 0.01, *** P ≤ 0.001 and **** p < 0.0001. auf, arbitrary units of fluorescence.

    Article Snippet: Recombinant His-tagged Spike S1 wild-type (#40591-V08B1), S1 Omicron (#40592-V08H121) or Spike S1/S2 TRIMER wild-type (#40589-V08H8), all from Sino Biological at a concentration of 0.25 mg/ml supplemented with phenol red were injected into the hindbrain (1 nl) of 48 hpf zebrafish larvae.

    Techniques: Variant Assay, Recombinant, Injection, Quantitative RT-PCR, Activity Assay, Fluorescence

    Omicron causes higher neutrophil cell death than the ancestral variant. Recombinant S1WT, S1 Omicron or vehicle (-) were injected in the hindbrain ventricle (HBV) of Tg(lyz:DsRED) (A, B) of 2-dpf larvae. Tunel positive neutrophil number (double positive) was counted at 6 hpi in the head and tail of the larvae (A, B) . Representative photos for each treatment are shown. Scale bar 500 μm. Each dot represents one individual, and the means ± SEM for each group is also shown. P values were calculated using one-way analysis of variance (ANOVA) and Tukey multiple range test. ns, not significant; * P ≤ 0.05, ** P ≤ 0.01 and **** p < 0.0001.

    Journal: Frontiers in Immunology

    Article Title: Dual role of ACE2 in regulating inflammation triggered by Omicron S1 and other SARS-CoV-2 Spike variants

    doi: 10.3389/fimmu.2025.1667880

    Figure Lengend Snippet: Omicron causes higher neutrophil cell death than the ancestral variant. Recombinant S1WT, S1 Omicron or vehicle (-) were injected in the hindbrain ventricle (HBV) of Tg(lyz:DsRED) (A, B) of 2-dpf larvae. Tunel positive neutrophil number (double positive) was counted at 6 hpi in the head and tail of the larvae (A, B) . Representative photos for each treatment are shown. Scale bar 500 μm. Each dot represents one individual, and the means ± SEM for each group is also shown. P values were calculated using one-way analysis of variance (ANOVA) and Tukey multiple range test. ns, not significant; * P ≤ 0.05, ** P ≤ 0.01 and **** p < 0.0001.

    Article Snippet: Recombinant His-tagged Spike S1 wild-type (#40591-V08B1), S1 Omicron (#40592-V08H121) or Spike S1/S2 TRIMER wild-type (#40589-V08H8), all from Sino Biological at a concentration of 0.25 mg/ml supplemented with phenol red were injected into the hindbrain (1 nl) of 48 hpf zebrafish larvae.

    Techniques: Variant Assay, Recombinant, Injection, TUNEL Assay

    Trimeric ancestral variant induces a weaker immune response than its monomeric form. Recombinant S1WT (monomeric), S1/S2WT-T (trimeric) or vehicle (-) were injected in the hindbrain ventricle (HBV) of Tg(lyz:DsRED) (A) , Tg(mfap4:Tomato) (B) , Tg( nfkb :eGFP) (C) 2-day postfertilization larvae (dpf). Neutrophil (A) and macrophage (B) recruitment and number and Nfkb reporter activity (C) were analyzed at 6, 12, and/or 24 hpi by fluorescence microscopy. Representative photos for each treatment are shown from 24 hpi. Scale bar 500 μm. Each dot represents one individual, and the means ± SEM for each group is also shown. P values were calculated using one-way analysis of variance (ANOVA) and Tukey multiple range test. ns, not significant; * P ≤ 0.05, ** P ≤ 0.01, *** P ≤ 0.001 and **** p < 0.0001. auf, arbitrary units of fluorescence.

    Journal: Frontiers in Immunology

    Article Title: Dual role of ACE2 in regulating inflammation triggered by Omicron S1 and other SARS-CoV-2 Spike variants

    doi: 10.3389/fimmu.2025.1667880

    Figure Lengend Snippet: Trimeric ancestral variant induces a weaker immune response than its monomeric form. Recombinant S1WT (monomeric), S1/S2WT-T (trimeric) or vehicle (-) were injected in the hindbrain ventricle (HBV) of Tg(lyz:DsRED) (A) , Tg(mfap4:Tomato) (B) , Tg( nfkb :eGFP) (C) 2-day postfertilization larvae (dpf). Neutrophil (A) and macrophage (B) recruitment and number and Nfkb reporter activity (C) were analyzed at 6, 12, and/or 24 hpi by fluorescence microscopy. Representative photos for each treatment are shown from 24 hpi. Scale bar 500 μm. Each dot represents one individual, and the means ± SEM for each group is also shown. P values were calculated using one-way analysis of variance (ANOVA) and Tukey multiple range test. ns, not significant; * P ≤ 0.05, ** P ≤ 0.01, *** P ≤ 0.001 and **** p < 0.0001. auf, arbitrary units of fluorescence.

    Article Snippet: Recombinant His-tagged Spike S1 wild-type (#40591-V08B1), S1 Omicron (#40592-V08H121) or Spike S1/S2 TRIMER wild-type (#40589-V08H8), all from Sino Biological at a concentration of 0.25 mg/ml supplemented with phenol red were injected into the hindbrain (1 nl) of 48 hpf zebrafish larvae.

    Techniques: Variant Assay, Recombinant, Injection, Activity Assay, Fluorescence, Microscopy

    Trimeric ancestral variant induces a weaker proinflammatory response than its monomeric form. Recombinant S1WT, S1/S2WT-T or vehicle (-) were injected in the hindbrain ventricle (HBV) of WT (A–E) 2-day postfertilization larvae (dpf). The transcript levels of the indicated genes (A–D) were analyzed at 12 hpi by RT-qPCR in larval head and rest of the body and caspase-1 activity was determined at 24 hpi using a fluorogenic substrate (E) . Graphs shown are representative of three independent experiments; technical replicates are displayed in each graph. The means ± SEM for each group is shown. P values were calculated using one-way analysis of variance (ANOVA) and Tukey multiple range test. n=40 in A-D, n=35 in E. ns, not significant; * P ≤ 0.05, ** P ≤ 0.01, *** P ≤ 0.001 and **** p < 0.0001. auf, arbitrary units of fluorescence.

    Journal: Frontiers in Immunology

    Article Title: Dual role of ACE2 in regulating inflammation triggered by Omicron S1 and other SARS-CoV-2 Spike variants

    doi: 10.3389/fimmu.2025.1667880

    Figure Lengend Snippet: Trimeric ancestral variant induces a weaker proinflammatory response than its monomeric form. Recombinant S1WT, S1/S2WT-T or vehicle (-) were injected in the hindbrain ventricle (HBV) of WT (A–E) 2-day postfertilization larvae (dpf). The transcript levels of the indicated genes (A–D) were analyzed at 12 hpi by RT-qPCR in larval head and rest of the body and caspase-1 activity was determined at 24 hpi using a fluorogenic substrate (E) . Graphs shown are representative of three independent experiments; technical replicates are displayed in each graph. The means ± SEM for each group is shown. P values were calculated using one-way analysis of variance (ANOVA) and Tukey multiple range test. n=40 in A-D, n=35 in E. ns, not significant; * P ≤ 0.05, ** P ≤ 0.01, *** P ≤ 0.001 and **** p < 0.0001. auf, arbitrary units of fluorescence.

    Article Snippet: Recombinant His-tagged Spike S1 wild-type (#40591-V08B1), S1 Omicron (#40592-V08H121) or Spike S1/S2 TRIMER wild-type (#40589-V08H8), all from Sino Biological at a concentration of 0.25 mg/ml supplemented with phenol red were injected into the hindbrain (1 nl) of 48 hpf zebrafish larvae.

    Techniques: Variant Assay, Recombinant, Injection, Quantitative RT-PCR, Activity Assay, Fluorescence